Molecular Recognition of Glycopolymer Interface
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چکیده
Saccharides on the cell surfaces play important roles in the living systems. For example, it mediate the cell-cell adhesion, fertilization, protein transportation, infection of pathogens and cancer metastasis etc [1, 2]. The saccharide-protein interactions also involve the various biological events (Table 1). Actualy, the saccharides are the model compounds of some of the medicines like oseltamivir [3]. The interaction between galactose and asialoglycoprotein receptor is a possible mechanism for the hepatocyte-specific drug delivery systems [4]. Therefore, it has been pointed out that the saccharide-protein interaction can be utilized for the novel bio-functional mateials such as cell cultivation, medicine target, and drug deliver‐ ly systems.
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تاریخ انتشار 2013